Preparation and Characterization of Polyvinyl Alcohol-Nano Hidroxyapatite using Gamma Iradiation Technique for Biomaterial

Yessy Warastuti, Dian Pribadi Perkasa, Erizal Erizal, Basril Abbas, Sudirman Sudirman

Abstract


ABSTRACT

The development and use of biomaterials in the biomedical field as bone implants are becoming increasingly important. Synthesis of polyvinyl alcohol (PVA) – bionanohydroxyapatite (HAp) composite hydrogel  has been carried using gamma irradiation technique. The PVA-HAp mixtures containing PVA (10-20%, w/v) and  a single concentration of HAp (20%w) were irradiated with various  irradiation doses  (0-20 kGy). The physico-chemical properties of irradiated composites were observed,includingmechanical properties, water absorption, biodegradation test, and characterized using Fourier-transform Infared Spectroscopy(FTIR), Transmission Electron Microscope (TEM)and Scanning Electron Microscopy (SEM). The results showed that the optimum  conditions wasPVA-HAp hydrogel composites (20%-20%, irradiation dose 20 kGy) with tensile strength 0.82 Mpa, elongation of 281.67%, water  absorption of 103.18%, and  biodegradation of 22.46%. The results of FTIR measurements of  PVA-HAp composites showed the occurrence of crosslinking  between PVA-HAp in the irradiation process. The SEM and TEM measurements showed that  HAp powder  was nano particle ( <60 mesh) and in the formed of fibers and with heterogen porousThe irradiated  PVA-HA composite  was expected to be  as candidate for  biomaterials application.


Keywords


biomaterial, PVA, hydroxyapatite, composite, gamma irradiation

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DOI: http://dx.doi.org/10.32537/jkgi.v27i1.4064

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