(Antioxidants : Mechanism of Action and Its Function in Human Body)

Hendra Wijaya, Lukman Junaidi

Abstract


Antioxidant could be defined by several means. Antioxidant is a substance that could postpone and delay oxidation of molecule substrate in human body ,i.e ; protein ,carboydtrate,lipid and DNA, by oxidant. antioxidant that works in the human body's biological system is called a  biological antioxidant Biological antioxidants can be grouped into :1) enzymatic antioxidants (endogenous) ,2) non-enzymatic antioxidants (endogenaous) and, 3) antioxidants from food (exogenous0.Enzymatic antioxidants (endogenous) include superoxide dismutase ,catalase ,glutathione peroxidase, glutaredoksin, tioredoksin, peroksiredoksin ,and coenzyme q10.non-enzymatic antioxidants (ENDOGENOUS) are carotenoids,vitamin E  and vitamin C those antioxidants are able to work in hydrophobic and hydrophilic cellular environment so as to from a strong network of cooperation in preventing the occurrence of oxidative damage .some of the functions of antioxidants in the human body that can be expressed are ; preventive defense the human body against oxidants ,strong defense system against free redicals ,prevent the occurrence atherosclerosis in blood vessels,regulation of metabolism such as disabling lipoksigenase.


Keywords


Bilogical antioxidant, endogeneous antioxidants, enzymatic antioxidants, non-enzymatic antioxidants exogeneous antioxidants

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DOI: http://dx.doi.org/10.32765/warta%20ihp.v28i02.2633

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